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FAMVIR® (famciclovir) is a prescription oral antiviral medication that is indicated for treatment of recurrent genital herpes, suppression of recurrent genital herpes, and treatment of recurrent herpes simplex virus infections (genital herpes and cold sores) in HIV-infected patients.
Famvir®
Important Note
The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.
Common Brand Name(s)
Famvir
Types
of Treatment
After the initial outbreak* of genital herpes, FAMVIR can
be prescribed in one of three ways:
- Episodic
treatment - your doctor treats an outbreak of genital
herpes as it occurs. The usual dose of FAMVIR is one 125-mg
pill, twice a day, for 5 days.?
- Suppressive
treatment ? if you have frequent or severe outbreaks,
you take one 250-mg pill, twice a day, for up to 1 year??
to suppress the genital herpes virus and help to prevent
outbreaks.
- Patients
with HIV - FAMVIR is the only prescription oral antiviral
therapy indicated for treating genital or orolabial herpes
in people infected with HIV. In patients with herpes simplex
and HIV, the dose of FAMVIR is 500 mg, twice a day, for
7 days.?
FAMVIR
can be taken with or without food.
When discussing
treatment options with your doctor, be sure to discuss your
lifestyle, how you feel about outbreaks, the pain and severity
of your symptoms, and the frequency of your outbreaks. Be
sure to talk with your doctor about the type of treatment
(episodic or suppressive) that would be most appropriate for
you.
For episodic
and suppressive treatment, always take your medicine as prescribed
by your doctor. If you are taking any other prescription or
over-the-counter medications, please be sure to tell your
doctor. No medication has been proven to prevent the transmission
of genital herpes. It's important to know that FAMVIR will
not prevent the spread of genital herpes to others. During
an outbreak, you must avoid sexual contact, and use a condom
in between outbreaks.
Efficacy
of FAMVIR
- Episodic
Treatment
One clinical study showed that episodic treatment with FAMVIR
significantly relieved all of the symptoms of a genital
herpes outbreak. For many people, the duration of the symptoms
associated with genital herpes, pain, burning, itching,
and tenderness, was reduced. These same people also experienced
a faster healing of sores compared to those taking a sugar
pill.
- Suppressive
Treatment
Many people on twice-daily suppressive therapy with FAMVIR
may go almost a year without experiencing an outbreak.
Side
Effects and Other Important Information
FAMVIR should not be taken by patients with known hypersensitivity
to the product, its components, and DENAVIR® (penciclovir
cream).
FAMVIR
has no clinically significant interactions with cimetidine,
allopurinol, theophylline, digoxin, or zidovudine (AZT).
Concurrent
use of FAMVIR with probenecid or other drugs significantly
eliminated by active renal tubular secretion may result in
increased plasma concentrations of penciclovir.
FAMVIR
does not contain any dyes.
FAMVIR
(famciclovir) is not for everyone. In clinical studies with
FAMVIR, the most commonly reported side effects included headache,
nausea, and diarrhea. Ask your doctor if FAMVIR is right for
you.? If you have kidney problems, your doctor will determine
if FAMVIR is appropriate, and if so, what the right dose is
for you. See the full Prescribing Information for more information
about FAMVIR.
* The
efficacy of FAMVIR has not been established for the treatment
of an initial outbreak of genital herpes infection.
? If you
have impaired kidney function, your doctor will determine
the appropriate dose for you.
? The
safety and efficacy of FAMVIR therapy beyond 1 year of treatment
have not been established.
No antiviral
has been proven to prevent the transmission of genital herpes.
There
is no cure for genital herpes.
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